Prosom (Estazolam)

Recommended dose: 1–2 mg taken orally at bedtime for adults. Elderly or debilitated patients should start with 0.5 mg to reduce the risk of over-sedation and falls.

• Take Prosom only when you are ready to go to sleep immediately and have at least 7–8 hours available before needing to be awake.
• Can be taken with or without food. Avoid taking after a heavy meal as it may delay onset.
• Do not take a second dose the same night under any circumstances.
• Swallow the tablet whole — do not crush or split it.
• Prosom is recommended for short-term use only (typically 7–10 days). Do not use longer than prescribed without consulting your doctor.
• Do not stop suddenly after extended use — consult your doctor before discontinuing to avoid withdrawal symptoms.

Generic: Estazolam
Brand: Prosom
Category: Benzodiazepine / Sedative-Hypnotic
Available Forms: Oral tablets
Available Strengths: 1 mg, 2 mg

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What is Prosom used for?
Prosom (Estazolam) is used for the short-term treatment of insomnia — specifically to help with difficulty falling asleep, frequent nighttime awakenings, and early morning waking. It is intended for use over 7–10 days only.

How long does Prosom take to work?
Prosom typically begins working within 15–30 minutes of taking the dose. Effects last approximately 6–8 hours, making it suitable for a full night of sleep.

What are common side effects?
Drowsiness, dizziness, weakness, headache, dry mouth, nausea, and next-morning grogginess. Elderly patients are particularly sensitive to these effects and should use the lowest effective dose.

Is Prosom addictive?
Yes. Estazolam is a Schedule IV controlled substance with a risk of physical and psychological dependence, especially with long-term use or doses higher than prescribed. It is intended for short-term use only under medical supervision.

Prosom vs Lunesta – what is the difference?
Both treat insomnia. Prosom (Estazolam) is a benzodiazepine with a longer half-life, effective for both sleep onset and sleep maintenance. Lunesta (Eszopiclone) is a non-benzodiazepine Z-drug that is FDA-approved for longer-term use, with a lower reported dependency risk.

Can Prosom cause serious side effects?
Rare but serious: severe respiratory depression (especially with opioids or alcohol), paradoxical reactions (increased agitation or anxiety), severe memory impairment, and life-threatening withdrawal seizures upon abrupt discontinuation. Seek emergency help immediately if any of these occur.

Is Prosom safe in pregnancy?
No. Estazolam is not recommended during pregnancy. It may cause neonatal withdrawal syndrome and respiratory depression in newborns. Avoid during pregnancy and breastfeeding — consult your doctor for safer alternatives.

How long does Prosom stay in your system?
Half-life is approximately 10–24 hours. Detectable in urine for 2–5 days with occasional use, and potentially longer with prolonged heavy use.

Can I take Prosom with food?
Yes. Prosom can be taken with or without food. However, avoid taking it after a large, high-fat meal as this may delay its sleep-inducing effect.

Can I drink alcohol with Prosom?
No. Combining Prosom with alcohol significantly increases CNS and respiratory depression, extreme sedation, and risk of dangerous next-day impairment. Strictly avoid alcohol during use.